The intensive care unit serves as a central hub for treating critically ill patients, with the essential responsibility of providing continuous monitoring and care for severe cases. However, the current vital sign monitoring systems used in most domestic ICUs mainly depend on wired equipment, which comes with various limitations. This paper presents a wireless vital sign monitoring system that can be comfortably worn on the patient′s wrist and fingertips to address this issue. This system is designed to collect real-time data on the patient′s body temperature, heart rate, and blood oxygen saturation levels. The collected data is then uploaded to both a mobile phone and a cloud-based database for easy access and display. Compared to the existing wired monitors, this device is compact, easy to wear, and enhances patient comfort and mobility. It also reduces physical contact with the equipment, decreasing the infection risk. During testing, one individual wore the wireless monitoring device alongside a Huawei smart band and a medical-grade finger-clip heart rate and blood oxygen monitor (considered the standard) while resting. The results indicated that the standard error for heart rate data from the wireless monitoring device was 0.15, while for blood oxygen data, it was 0.065. In contrast, the Huawei smart band showed a standard error of 0.48 for heart rate data and 0.13 for blood oxygen data. These findings suggest that the wireless monitoring device provides greater measurement accuracy than the Huawei smart band and outperforms the finger-clip heart rate and blood oxygen monitor in terms of continuous monitoring and data recording capabilities. This advancement is significant for the evolution of intelligent ICUs.