When using terahertz timedomain spectroscopy(THzTDS) technology to perform quantitative analysis of nitrile rubber additives, the paper extending the partial least squares(PLS) to multidimensional partial least squares method(NPLS), which can solve the problem of high dimensional data modeling effectively and improve the model accuracy. To verify the effectiveness of the proposed algorithm above, PLS method and NPLS method are used respectively on sample modeling and analysis. Which obtained the root mean square error and the correlation coefficient of NPLS model is 2.04% and 0.98. While The root mean square error and the correlation coefficient ofPLS model is 2.71% and 0.97. The results show that both methods can forecast the content of some components in the mixture, but the prediction effect of NPLS model is better.