To accurately obtain the dynamic loads of the helicopter tail rotor within the flight envelope and address the challenges of low reliability in traditional slip rings and wired telemetry technologies, wiring difficulties, and insufficient synchronization accuracy, this paper developed a four-channel tail rotor load measurement system integrating wireless transmission and high-precision clock synchronization technologies. The system consists of a wireless load collector deployed on the rotating components of the tail rotor and a load receiver in the cabin, transmitting data via an RF link. It employs a global time reference based on inter-range instrumentation group time code B signal synchronization and an optimized master-slave clock synchronization algorithm, combined with dynamic timestamp alignment and strain measurement temperature compensation techniques, aiming to achieve microsecond-level data synchronization. Experimental results demonstrate that the constructed four-channel measurement system achieved an overall average synchronization accuracy of 1 060.5 ns, with the best channel reaching an average synchronization accuracy of 799 ns. Each strain measurement channel exhibited excellent linearity and measurement accuracy within the range of ±10 000 με, with the root mean square error of the average code values all below 3.9, meeting the requirements for flight tests.