Aiming at the problems of the insensitivity and inaccuracy of conventional controllers when the prpton exchange membrane fuel cell (PEMFC) power is high and the load current changes dynamically, a variable universe fuzzy PID control strategy was proposed in this paper. The proportion factor and scale factor in the fuzzy PID controller can be adjusted in real time by the factor to realize the contraction-expansion of the fuzzy universe, thereby improving the stability of the control. Build a 55KW fuel cell model and verify the feasibility of the model. Comparative experiments between the traditional control strategy and the variable universe fuzzy PID controll strategy. The research results indicate that the variable universe fuzzy PID controller is superior to the traditional controller in the overshoot, the steady-state error, the adjustment time, and the anti-interference performance.