In order to meet the requirements of real-time monitoring output voltage and output current of power supply and distribution control equipment of measurement system. This paper designs a high-precision current measurement circuit, which is based on TI's precision current monitor INA260, which can realize real-time monitoring and accurate measurement of 0-15A continuous current in the 0-36V power supply range. The current measurement value is output through the I2C interface, and the signal measurement circuit is electrically isolated from the digital control circuit. Through a large number of data tests, the error range between the measured output voltage and the theoretical value is 0~10mV, and the error range between the measured output current and the theoretical value is 0~5mA. The experimental results show that the application circuit's current measurement accuracy within 0~15A and voltage measurement accuracy within 0~36V are better than 1‰, realizing the function of real-time monitoring and improving the measuring precision.