Aiming at the problems that the discrete components used in the traditional missile-borne telemetry communication system occupy a large proportion of space and have poor portability, a software radio zero-IF telemetry transmitter system based on ZYNQ and AD9364 is designed. The system can perform DQPSK modulation on the data collected and framed by the editor, and use the PS terminal to configure the AD9364 registers. The modulated data is transmitted through the LVDS high-speed data interface between the PL and AD9364, and the up-conversion is completed inside the AD9364 chip. After processing, filtering, etc., the data is sent to the ground receiving station using the designed flexible antenna through the power amplifier module. Finally, a telemetering transmitter test system was built, and the telemetering transmitter was tested for modulation and communication, and the system's field data transmission and reception test was realized. Tests show that the system effectively reduces the size, power consumption and weight of the missile-borne telemetry system, and relying on powerful software reconfigurability, not only simplifies the hardware design, but also improves the versatility of the equipment, and the transmission distance is also greatly increased. It meets the miniaturization and versatility requirements of the missile-borne telemetry system.