In view of the serious harm of propellant leakage, a monitoring alarm system for propellant leakage based on CC2530 microcontroller and ZigBee wireless technology is proposed in this paper. The system mainly consists of wireless propellant leakage monitoring gas sensor, dual mode monitoring alarm host and master computer. The sensor and the alarm host transmit the signal through the ZigBee wireless technology. The alarm host and the master computer in the monitoring room transmit the data collected by the alarm host through Ethernet. The experimental results show that the wireless transmission of the system is reliable, and the monitoring error of propellant is less than 3%. The system realizes the wireless monitoring of propellant leakage, greatly reduces the installation time of the system, and has a strong mobility, not only realizes the fixed mode propellant leakage monitoring, but also realizes the leakage monitoring under the maneuver mode.